Tumor necrosis factor production inhibitors

Details Tumor necrosis factor production inhibitors Tumor necrosis factor production inhibitors

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2138305

There is provided a composition for inhibiting the production or secretion of tumor necrosis factor effective for the treatment of cachexia, septic shock, multiple organ failure, Rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, osteoarthritis, Behçet disease, systemic lupus erythematosus (SLE), graft versus host disease (GvHD), malaria, acquired immune deficiency syndrome (AIDS), meningitis, hepatitis and Type II diabetes mellitus. The composition comprises a pharmaceutically effective amount of a compound of formula (1).

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