Tumor-specific genomic instability as a prognostic indicator

Details Tumor-specific genomic instability as a prognostic indicator Tumor-specific genomic instability as a prognostic indicator

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2156920

A method for assessing the level of genomic instability in a malignant tumour is described. The method involves comparison of the structure of one or more interspersed repetitive sequence loci in tumor and corresponding normal tissue samples. Microsatellite repetitive sequences are one useful form of interspersed repetitive sequence that may be employed to characterize the genomic instability associated with some malignant tumors. This assessment provides an additional prognostic indicator for patients having such malignant tumors.

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