Tumor specific glycoproteins and method for detecting...

C - Chemistry – Metallurgy – 07 – K

Patent

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167/129, 167/40

C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/574 (2006.01)

Patent

CA 1087979

ABSTRACT OF THE DISCLOSURE A new class of glycoproteins has been found to be produced by human cancer cells and is not produced by normal cells and said glycoprotein is present in the sera of cancer patients. This tumor specific glycoprotein can be characterized by its isoelectric point of from about 4.2 to 4.6 and by the perchloric acid soluble fraction thereof having a sialic acid content of above about 0.065 mg/ml of initial serum sample. The presence of a tumorigenic cancer in a patient can be determined by detecting the presence of the tumor specific glycoprotein in the blood sera of a patient.

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