Tumor suppressor gene merlin and uses thereof

Details Tumor suppressor gene merlin and uses thereof Tumor suppressor gene merlin and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2115404

Tumor Suppressor Gene Merlin And Uses Thereof Abstract A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin- associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.

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