Tumor targeting agents and uses thereof

Details Tumor targeting agents and uses thereof Tumor targeting agents and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61P 35/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2500830

This invention relates to novel tumor targeting motifs, units and agents, as well as tumor targeting peptides and ana-logues thereof. The targeting agents typically comprise at least one targeting motif, Aa-Bb-Cc, and at least one ef- fector unic. The invention further relates to specific tumor targeting peptides, pharmaceutical and diagnostic com-posisitons comprising such peptides. Disclosed are also methods for diagnosing or treating cancer.

L'invention concerne de nouveaux motifs structuraux, unités et agents de ciblage tumoral, ainsi que des peptides de ciblage tumoral et des analogues de ceux-ci. Ces agents de ciblage comprennent généralement au moins un motif structural de ciblage Aa-Bb-Cc et au moins une unité effectrice. L'invention concerne en outre de nouveaux peptides de ciblage tumoral spécifiques, et des compositions pharmaceutiques et diagnostiques contenant de tels peptides. L'invention concerne également des méthodes de diagnostic ou de traitement des cancers.

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