Tumour-associated peptides that bind to mhc molecules

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 14/71 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 9/00 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2487137

The invention relates to a tumour-associated peptide containing an amino acid sequence, which is selected from the group consisting of SEQ ID No. 1 to SEQ ID No. 79 of the enclosed sequence protocol. Said peptide has the capacity to bond to a molecule of the human major histocompatibility complex (MHC) class I. The invention also relates to the use of the peptides for producing a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.

La présente invention concerne un peptide associé aux tumeurs qui présente une séquence d'acides aminés choisie dans le groupe formé par les séquences SEQ ID-Nr. 1 à SEQ ID-Nr. 79 du protocole de séquence ci-joint. Ce peptide a la capacité de se lier à une molécule du complexe majeur d'histocompatibilité (CMH) humain de classe I. La présente invention concerne également l'utilisation de ces peptides pour produire un médicament et pour traiter des maladies tumorales. En outre, cette invention concerne une composition pharmaceutique qui comprend au moins un desdits peptides.

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