Tumour localising photosensitising compounds

Details Tumour localising photosensitising compounds Tumour localising photosensitising compounds

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/40 (2006.01) A61K 31/785 (2006.01) A61K 41/00 (2006.01)

Patent

CA 2245202

The invention provides compounds comprising polyethylene glycol derivatised, pharmaceutically acceptable, tumour locating dihydro or tetrahydro porphyrins of the formulae (3), (4), and (4') wherein R1 may be partly hydroxyl but in at least one position is a chain of formula -O-X-[CH2CH2O]m-Y wherein m = 25 to 150, Y is a C1 -C4 alkyl group but preferably a methyl group and the group X is of formula (5a) or (5b).

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