Tumour suppressor protein

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01)

Patent

CA 2547626

We describe a polypeptide which binds and modulates the activity of a tumor suppressor polypeptide, for example p53; a nucleic acid molecule encoding said protein and screening methods which modulate the binding activity of said polypeptide for its target polypeptide(s).

La présente invention concerne un polypeptide qui lie et module l'activité d'un polypeptide de suppression des tumeurs, par exemple, p53; une molécule d'acide nucléique qui code ladite protéine et des méthodes de criblage permettant de moduler l'activité de liaison dudit polypeptide pour son ou ses polypeptides cibles.

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