Tumour treatment

Details Tumour treatment Tumour treatment

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61P 35/00 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2537783

The invention provides a method of treating an IGF-activated tumour in a subject in need of such treatment, said method comprising administering to said subject an effective amount of an expression cassette comprising a polynucleotide encoding an IGFBP4 (Insulin-like Growth Factor Binding Protein 4) polypeptide operably linked to a muscle-specific regulatory element, such that said polynucleotide is expressed in said tumour to form said polypeptide.

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