Tumour vaccine comprising allogeneic or xenogeneic tumour cells

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2637690

The present invention provides a composition for the treatment of a tumour, comprising: (i) allogeneic or xenogeneic tumour cells; and (ii) a pharmaceutically acceptable excipient. If two or more heterozygous individuals have the same cancer/tumour of the same or similar histological grade, then transplantation of tumour/cancer tissue/cells from one individual to another will not only induce rejection of the transplanted tissue/cancer, but will also increase the immunological awareness of the immune system to peptides shared between the tumours/cancers and other tumours possessing similar peptides.

La présente invention concerne une composition destinée au traitement d'une tumeur, comprenant : (i) des cellules tumorales allogèniques ou xénogèniques ; et (ii) un excipient pharmaceutiquement acceptable. Si au moins deux individus hétérozygotes ont un cancer/une tumeur identique ayant un degré histologique identique ou similaire, la transplantation de tissus/cellules tumoraux/cancéreux d'un individu à un autre induira non seulement le rejet du tissu/cancer transplanté mais augmentera aussi la vigilance immunologique du système immunitaire vis-à-vis de peptides communs aux tumeurs/cancers et à d'autres tumeurs possédant des peptides similaires.

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