Tylosin resistance-conferring gene, designated tlrb, for use...

Details Tylosin resistance-conferring gene, designated tlrb, for use... Tylosin resistance-conferring gene, designated tlrb, for use...

C - Chemistry, Metallurgy

12

N

195/1.22, 195/1.

C12N 15/00 (2006.01) C12N 15/52 (2006.01) C12N 15/76 (2006.01)

Patent

CA 1280703

X-6728 Abstract The tlrB gene is a novel tylosin resistance- conferring gene isolated from Streptomyces fradiae and used to construct a number of cloning vectors for use in Streptomyces and related organisms. One such cloning vector, plasmid pSVB9, can be obtained in S. lividans under the accession number NRRL 18037. S. lividans is the preferred host when the tlrB gene is used to select tylosin-resistant Streptomyces transformants.

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