Type 2 cytokine receptor and nucleic acids encoding same

Details Type 2 cytokine receptor and nucleic acids encoding same Type 2 cytokine receptor and nucleic acids encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 31/7088 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2464765

The present invention provides novel isolated CRF2-13 polynucleotides and polypeptides encoded by the CRF2-13 polynucleotides. Also provided are the antibodies that immunospecifically bind to a CRF2-13 polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the CRF2-13 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the CRF2-13 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne de nouveaux polynucléotides isolés CRF2-13 et des polypeptides codés par lesdits polynucléotides CRF2-13; des anticorps qui se lient de manière immunospécifique à un polypeptide CRF2-13 ou à n'importe quel dérivé (y compris un dérivé de fusion), variant, mutant ou fragment du polypeptide, polynucléotide ou anticorps CRF2-13. Cette invention concerne également des méthodes dans lesquelles on utilise le polypeptide, le polynucléotide ou l'anticorps CRF2-13 pour détecter et traiter une grande diversité d'états pathologiques, ainsi que d'autres utilisations de ces derniers.

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