C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) C07K 14/71 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2044626
Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to pro- duce a hitherto unknown type of human Platelet-Derived Growth Factor (PDGF) receptor protein (see genetic map, figure 2) free of other PDGF receptors. These proteins can be produced from DNA segments in cells in various functional forms. These forms variously enable biochemical and functional studies of these novel receptors as well as production of antibodies. Means are de- scribed for determining the level of expression of genes for specific types of PDGF receptor proteins, for example, by measuring mRNA in cell with PDGF receptor type-specific DNA probes or by measuring antigene in biological samples with type-specific antibodies.
Aaronson Stuart A.
Matsui Toshimitsu
Pierce Jacalyn H.
Macrae & Co.
The United States Of America As Represented By The Secretary Department Of Health And Human Services
The United States Of America As Represented By The Secretary U.s
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