Type f botulinum toxin and use thereof

Details Type f botulinum toxin and use thereof Type f botulinum toxin and use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/08 (2006.01) C07K 1/22 (2006.01) C07K 14/33 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2224444

A polypeptide free of toxin activity gives protection against botulinum type F toxin. A fusion protein of a fragment of a toxin molecule and a purification moeity enables purification of the fragment from solution. Pharmaceutical compositions containing the polypeptide and the fusion protein are described.

Un polypeptide dépourvu d'activité toxinique présente une protection contre la toxine botulinique de type F. Une protéine de fusion d'un fragment d'une molécule de toxine ainsi qu'une fraction de purification permettent la purification du fragment à partir de la solution. L'invention se rapporte également aux compositions pharmaceutiques contenant le polypeptide et la protéine de fusion.

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