Type i and type ii surface antigens associated with...

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A61K 39/085 (2006.01) A61K 39/40 (2006.01) C07K 16/12 (2006.01) C12P 19/04 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2123811

A process is disclosed for culturing clinical Staphylococcus epidermidis cells that reproducibly enables identification of a limited number of predominant serotypes. Two predominant serotypes common to most clinical cases of S. epidermidis have been identified and are denoted Type I and Type II. A particular polysaccharide surface antigen is associated with each of the Type I and Type II serotypes. The surface antigens can be used to provide active and passive immunization against S. epidermidis infection and to produce a hyperimmune immunoglobulin or antibodies for treatment of S. epidermidis infection.

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