Type i angiotensin ii receptor specific monoclonal...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/18 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2170606

The present invention relates to a novel hybridoma cell line which secretes monoclonal antibodies capable of binding to the AT1 subtype of the Angiotensin II receptor. It also relates to monoclonal antibodies secreted by the hybridoma, which antibodies may be used in diagnostic test kits as well as having therapeutic applications.

L'invention se rapporte à une nouvelle lignée cellulaire d'hybridome qui secrète des anticorps monoclonaux capables de se fixer au récepteur du sous-type AT¿1? de l'angiotensine II. L'invention se rapporte également aux anticorps monoclonaux sécrétés par l'hybridome que l'on peut utiliser dans des nécessaires pour tests diagnostiques, ces anticorps ayant également des applications thérapeutiques.

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