Type ii tgf-beta receptor/immunoglobulin constant region...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 38/17 (2006.01) C07K 14/71 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2286933

Fusion proteins comprising the TGF-beta Type II receptor linked to a portion of an immunoglobulin constant chain are described. Also described are methods of using the fusion proteins of the invention to treat a variety of fibroproliferative disorders.

On décrit de protéines hybrides contenant le récepteur type II du TGF-bêta lié à une partie d'une chaîne constante d'immunoglobuline, ainsi que des procédés d'utilisation desdites protéines pour traiter un grand nombre d'affections fibronéoplastiques.

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