C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/21 (2006.01) A61K 38/00 (2006.01) A61K 39/104 (2006.01) A61K 39/395 (2006.01) A61P 31/04 (2006.01) C07K 16/12 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2709500
An object is to provide an antibody and a vaccine composition which have an ability to practically prevent or treat a Pseudomonas aeruginosa infection, and which can cope with the diversity of clinical isolates derived from patients infected with Pseudomonas aeruginosa. According to the present invention, an antibody against a PA1698 protein that is a type III secretion system component protein of Pseudomonas aeruginosa or against a peptide of the protein, and a vaccine composition comprising the protein or the peptide are provided.
L'invention porte sur un anticorps et sur une composition de vaccin qui sont capables d'empêcher ou de traiter sensiblement une infection par le Pseudomonas aeruginosa et qui sont applicables à une grande diversité de souches cliniquement isolées de Pseudomonas aeruginosa provenant de patients souffrant de l'infection par le Pseudomonas aeruginosa. Plus précisément, l'invention porte sur un anticorps dirigé contre la protéine PA1698 qui est une protéine composante pour le système de sécrétion de type-III de Pseudomonas aeruginosa ou un peptide de la protéine ; et sur une composition de vaccin comportant la protéine ou le peptide.
Akabane Hirotomo
Kumagai Masashi
Nagaso Hiroshi
Ninomiya Tomohisa
Otsuka Keiko
Fetherstonhaugh & Co.
Meiji Seika Kaisha Ltd.
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