Type s3n2 chelators for radioactive isotopes, their metal...

Details Type s3n2 chelators for radioactive isotopes, their metal... Type s3n2 chelators for radioactive isotopes, their metal...

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01) A61K 51/08 (2006.01) C07B 59/00 (2006.01) C07F 13/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 7/64 (2006.01) C07K 16/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2156641

36 S u m m a r y This invention relates to new bifunctional chelating agents with intermittent chalcogen atoms, pharmaceuticals containing these compounds, their use in radiodiagnostics and radiotherapy, and methods for the production of these compounds. The compound according to the invention has the general formula (I) M - L wherein M represents a radionuclide of Tc or Re and L a ligand of the general formula (II). It was found, surprisingly, that these new, bifunctional chelating agents with intermittent chalcogen atoms and their coupling products with compounds that accumulate specifically are excellently suited for producing radio- pharmaceuticals for diagnostic and therapeutic purposes.

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