C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2717509
The present invention is directed to low molecular weight and orally bioavailable 3H-[1,2,3]triazolo[4,5-d]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the tyrosine kinase MET. The invention is also directed to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
La présente invention porte sur des dérivés de 3H-[1,2,3]triazolo[4,5-d]pyrimidine de faible masse moléculaire et biodisponibles par voie orale, qui sont utiles pour traiter des maladies prolifératives cellulaires, pour traiter des troubles associés à une activité de MET, et pour inhiber la tyrosine kinase MET. L'invention porte également sur des compositions qui comprennent ces composés, et sur des procédés les utilisant pour traiter le cancer chez les mammifères.
Borden Ladner Gervais Llp
Tiger Pharmatech
LandOfFree
Tyrosine kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tyrosine kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tyrosine kinase inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1516002