A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) C07D 243/10 (2006.01)
Patent
CA 2624353
The present invention relates to pyrido[3,2-c]benzazocinone derivatives and related compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
La présente invention se rapporte à des dérivés de pyrido[3,2-c]benzazocinone et à des composés associés, qui sont utiles pour traiter des maladies liées à la prolifération cellulaire, pour traiter des troubles associés à l'activité de MET, et pour inhiber le récepteur tyrosine kinase MET. L'invention a également trait à des compositions qui contiennent lesdits composés, et à leurs procédés d'utilisation pour traiter le cancer chez des mammifères.
Dinsmore Christopher J.
Lim Jongwon
Northrup Alan B.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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