Tyrosine kinase inhibitors

Details Tyrosine kinase inhibitors Tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01) C07D 491/056 (2006.01) C07D 495/04 (2006.01) C07D 497/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2387840

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

L'invention concerne des composés qui inhibent, régulent et/ou modulent la transduction de signal de tyrosine kinase, ainsi que des compositions renfermant ces composés, et des procédés d'utilisation de ces derniers pour traiter, chez le mammifère, les maladies et conditions dépendant de la tyrosine kinase, telles que l'angiogénèse, le cancer, la croissance tumorale, l'athérosclérose, la dégénération maculaire liée au vieillissement, la rétinopathie diabétique et les maladies inflammatoires, entre autres.

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