C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/22 (2006.01) A61K 31/439 (2006.01) A61P 35/00 (2006.01) C07D 471/08 (2006.01)
Patent
CA 2480754
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non- receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
La présente invention concerne des composés qui peuvent inhiber, moduler et/ou réguler la transduction de signaux de tyrosine kinases de type récepteur et de type non récepteur. Les composés de cette invention possèdent une structure centrale qui contient un groupe caractéristique de benzazocine. Cette invention a également trait à des sels acceptables pharmaceutiquement, à des hydrates et à des stéréoisomères de ces composés.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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