Tyrosine kinase inhibitors

Details Tyrosine kinase inhibitors Tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/551 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2483084

The present invention relates to imidazopyridine compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

La présente invention se rapporte à des composés d'imidazopyridine inhibant, régulant et/ou modulant la transduction des signaux de tyrosine kinase, à des compositions contenant ces composés ainsi qu'à leurs procédés d'utilisation dans le traitement de maladies et de troubles influencés par la tyrosine kinase, notamment l'angiogenèse, le cancer, la croissance tumorale, l'athérosclérose, la dégénérescence maculaire liée à l'âge, la rétinopathie diabétique, les maladies inflammatoires et analogues chez les mammifères.

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