Tyrosine kinase inhibitors

Details Tyrosine kinase inhibitors Tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/422 (2006.01) A61K 31/427 (2006.01) A61K 31/433 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2384101

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

La présente invention concerne des composés qui inhibent, régulent et/ou modulent la transduction de signaux de tyrosines kinases, des compositions contenant ces composés, et des procédés destinés à leur utilisation pour le traitement de maladies et de troubles dépendant des tyrosines kinases, tels que l'angiogenèse, le cancer, la croissance tumorale, l'athérosclérose, les dégénérescences maculaires liées à l'âge, la rétinopathie diabétique, les maladies inflammatoires, et les maladies du même type chez les mammifères.

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