Tyrosine kinase inhibitors

Details Tyrosine kinase inhibitors Tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/435 (2006.01) A61K 31/4355 (2006.01) A61K 31/4365 (2006.01) C07D 471/04 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2400875

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

L'invention concerne des composés qui inhibent, régulent et/ou modulent la transduction de signal de la tyrosine kinase, des compositions contenant ces composés, ainsi que des méthodes les utilisant pour traiter des troubles et conditions modulés par la tyrosine kinase, tels que l'angiogénèse, le cancer, la croissance de tumeur, l'athérosclérose, la maculopathie liée à l'âge, la rétinopathie diabétique, des maladies inflammatoires et d'autres troubles et conditions, chez les mammifères.

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