Tyrosine kinase negative trkb

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/13, 195/1.22

C12N 15/12 (2006.01) C07K 14/82 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2040099

DC3 ABSTRACT OF THE DISCLOSURE TYROSINE KINASE NEGATIVE TRKB Nucleic acid sequences, particularly DNA sequences, coding for all or part of a tyrosine kinase negative trkB protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods for detecting the DNA sequences or the corresponding RNA sequences. The invention also concerns polypeptide molecules comprising all or part of a trkB protein that lacks a catalytic tyrosine protein kinase domain (tyrosine kinase negative trk.beta. protein).

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