Tyrosyl derivatives and their use as p2x7 receptor modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61K 31/4985 (2006.01) A61K 31/506 (2006.01) A61K 45/06 (2006.01) C07D 217/04 (2006.01) C07D 401/12 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2471562

The present invention relates to tyrosyl derivatives and their pharmaceutically acceptable salts; compositions thereof and methods of preparing the compounds are also described. The compounds are useful in the treatment of diseases in mammals that are mediated by the action of the P2X7 receptor.

La présente invention porte sur des dérivés de tyrosyle et sur leurs sels acceptables d'un point de vue pharmaceutique; sur leurs compositions et sur des procédés de préparation de composés. Les composés sont utiles dans le traitement de maladies affectant des mammifères par l'action du récepteur P2X¿7?.

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