Tyrphostins for treatment of allergic, inflammatory and...

A - Human Necessities – 61 – K

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167/233, 167/258

A61K 31/415 (2006.01) A61K 31/00 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2012634

TYRPHOSTINS FOR TREATMENT OF ALLERGIC, INFLAMMATORY AND CARDIOVASCULAR DISEASES ABSTRACT OF THE INVENTION This invention pertains to the novel use of composi- tions useful in the treatment of inflammation induced diseases comprising: (a) a compound of the formula: Image wherein R1 is H, OH, OCH3, ETO; R2 is EtO, CHC(CH3)2, iso-Proline, CH3SCH2, H, OH, NO2, OCH3, OCH, R6Cl; R3 is H, OH, OCH3, phenyl SCH2, CH.(CH3)2, iso-Proline, CH3SCH2; R4 is H, OH; R5 is H, CN, COOH, NHCHO; R6 is H, CN, COOH, NHCHO, O, S; R7 is H, OH; and wherein R5 and R6 include cyclic structures, and pharmaceutically acceptable acid addition salts thereof; and (b) a pharma- ceutically acceptable carrier.

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