C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C12N 9/64 (2006.01)
Patent
CA 2534481
The present invention provides novel members of the family of deubiquitinating enzymes (DUBs) as well as biologically, diagnostically or therapeutically useful fragments, derivatives, and homologues thereof, which are useful in research, biological, clinical, therapeutic as well as prognostic and diagnostic purposes. Furthermore, the polynucleotides and polypeptides provided by the present invention are useful for the treatment and diagnosis of breast cancer, leukemia or brain disorders.
La présente invention concerne de nouveaux membres de la famille des enzymes de désubiquitination (DUB) ainsi que des fragments, des dérivés et des homologues de celles-ci biologiquement, diagnostiquement ou thérapeutiquement utiles, notamment à des fins de recherche, biologiques, cliniques, thérapeutiques et à des fins pronostiques et diagnostiques. En outre, les polynucléotides et polypeptides concernés par la présente invention sont utiles pour le traitement et le diagnostic du cancer du sein, de la leucémie ou de troubles cérébraux.
Bruengger Adrian
Cai Richard Lie
Kossida Sophia
Nirmala Nanguneri R.
Pierrat Benoit
Fetherstonhaugh & Co.
Novartis Ag
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