C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/02 (2006.01) A61K 31/335 (2006.01) C07D 303/36 (2006.01) C07D 303/46 (2006.01) C12N 1/20 (2006.01)
Patent
CA 2041237
Compounds UCF1 and derivatives thereof exhibit anti-bacterial and anti-tumour activities and may be used for the preparation of anti-bacterial and anti- tumour agents. Compounds UCF1 may be produced by fermentation of a microorganism of the genus Streptomyces capable of producing compounds UCF1, preferably Streptomyces sp. UOF1 (FERM BP-2844) and recovering the desired compounds from the cultured broth. The compounds UCF1 have the formula Image (I) [wherein R represents either Image or Image The compounds may be oxidised to obtain derivatives of formula Image which exhibit similar pharmacological activities.
Hara Mitsunobu
Ikuina Yoji
Nakano Hirofumi
Okabe Masami
Saito Yutaka
Kirby Eades Gale Baker
Kyowa Hakko Kogyo Kabushiki Kaisha
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