C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12P 19/44 (2006.01) C12P 19/60 (2006.01)
Patent
CA 2702035
The present invention provides a novel UDP-glucuronosyltransferase and a polynucleotide encoding the same (for example, a polynucleotide comprising a polynucleotide consisting of one nucleotide sequence selected from the group consisting of the nucleotide sequence at positions 1 to 1359 in the nucleotide sequence represented by SEQ ID NO: 4, the nucleotide sequence at positions 1 to 1365 in the nucleotide sequence represented by SEQ ID NO: 10, the nucleotide sequence at positions 1 to 1371 in the nucleotide sequence represented by SEQ ID NO: 12, and the nucleotide sequence at positions 1 to 1371 in the nucleotide sequence represented by SEQ ID NO: 22; or a polynucleotide comprising a polynucleotide encoding a protein having one amino acid sequence selected from the group consisting of SEQ IDNOS: 5, 11, 13 and 23), etc. This provides a novel UDP-glucuronosyltransferase with a broad substrate specificity.
La présente invention vise à proposer une nouvelle UDP-glucuronyl transférase et un polynucléotide codant pour celle-ci (par exemple un polynucléotide contenant un polynucléotide comprenant une séquence nucléotidique choisie dans le groupe constitué par une séquence nucléotidique entre les positions 1 à 1359 de SEQ ID NO : 4, une séquence nucléotidique entre les positions 1 à 1365 de SEQ ID NO : 10, une séquence nucléotidique entre les positions 1 à 1371 de SEQ ID NO : 12 et une séquence nucléotidique entre les positions 1 à 1371 de SEQ ID NO : 22 ; ou un polynucléotide contenant un polynucléotide codant pour une protéine ayant une séquence d'acides aminés choisie dans le groupe constitué par SEQ ID NOS : 5, 11, 13 et 23), etc. Ceci fournit une nouvelle UDP-glucuronyl transférase à large spécificité de substrat.
Fukui Yuko
Mizutani Masako
Noguchi Akio
Ono Eiichiro
Fetherstonhaugh & Co.
Suntory Holdings Limited
LandOfFree
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