Ultra-pure human interleukin-6

Details Ultra-pure human interleukin-6 Ultra-pure human interleukin-6

C - Chemistry, Metallurgy

07

K

C07K 14/54 (2006.01) A61K 38/20 (2006.01) C07K 1/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2113868

ABSTRACT Essentially pure human interleukin-6 having a purity of at least 98 % as determined by single peak migration using capillary electrophoresis is obtained by a 3-step purification method which includes a cation-exchange chromatography step, a hydrophobic chromatography step and a reverse-phase chromatography step in the presence modifier.

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