Ultrasensitive detection of target using target-ready particles

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C08G 61/12 (2006.01) C08L 65/00 (2006.01) C09D 165/00 (2006.01) C40B 30/04 (2006.01) C40B 70/00 (2006.01)

Patent

CA 2692882

The invention relates to methods and reagents for detecting minute amounts of targets having affinity for nucleic acid. The present invention more particularly relates to target detection using aggregates of cationic polymer chains and nucleic acid capture probes linked to particles, such as controllable mobility particles.

L'invention porte sur des procédés et des réactifs permettant de détecter des quantités minuscules de cibles présentant une affinité pour un acide nucléique. Plus particulièrement, la présente invention porte sur la détection de cible par agrégats de chaînes polymères cationiques et sondes de capture d'acide nucléique reliés aux particules, telles que des particules à mobilité contrôlable.

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