C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 13/00 (2006.01) C12N 5/071 (2010.01) A61L 27/36 (2006.01) A61N 7/00 (2006.01) C12M 1/42 (2006.01)
Patent
CA 2526500
The present invention provides a method of, and apparatus for, utilising ultrasonic energy so as to mechanically disrupt the collagenous architecture of biological matrices in a controlled manner so that the tissue can be rapidly recellularised in continuous form. The present invention also provides for the production of tissue matrices with improved recellularisation properties, cell stratification or patterning.
L'invention concerne un procédé et un appareil d'utilisation d'énergie ultrasonore permettant de produire une rupture mécanique de l'architecture collagène de matrices biologiques de manière contrôlée de façon que les tissus soient rapidement recellularisés en continu. L'invention concerne également la production de matrices de tissus présentant des propriétés améliorées de recellularisation, de stratification cellulaire ou de formation de motifs.
Fisher John
Ingham Eileen
Ridout & Maybee Llp
University Of Leeds
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