Ultrasound-activated anti-infective coatings and devices...

A - Human Necessities – 61 – L

Patent

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A61L 29/16 (2006.01)

Patent

CA 2578833

An implantable medical device is provided including a vascular access device and a coating on at least one of an inner surface and an outer surface of the vascular access device. The coating includes: (a) a polymeric component including at least one of a light reactive moiety and a sound reactive moiety; and (b) at least one therapeutic agent releasably associated with the polymeric component, wherein a rate of release of the therapeutic agent is controlled by in situ exposure of the medical device to at least one of a light energy source and an ultrasound energy source.

Un dispositif médical pouvant être implanté est fourni, lequel inclut un dispositif d'accès vasculaire et un revêtement sur au moins l'une des surfaces intérieures et des surfaces extérieures du dispositif d'accès vasculaire. Le revêtement inclut : (a) un composant polymère incluant au moins un fragment réactif à la lumière et un fragment réactif au son et (b) au moins un agent thérapeutique associé avec une possibilité de libération du composant polymère, où la vitesse de libération de l'agent thérapeutique est régulée par une exposition in situ du dispositif médical à au moins l'une des sources d'énergie lumineuse et des sources d'énergie à ultrasons.

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