Ultrasound-enhanced delivery of materials through the skin

Details Ultrasound-enhanced delivery of materials through the skin Ultrasound-enhanced delivery of materials through the skin

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61K 9/00 (2006.01) A61N 7/00 (2006.01) A61B 10/00 (2006.01) A61B 17/00 (2006.01) A61N 1/30 (2006.01)

Patent

CA 2075624

A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.

Une méthode pour accroître la perméabilité de la peau ou d'une autre membrane biologique à une substance, comme un médicament, est divulguée. Dans cette méthode, le médicament est administré à l'aide d'ultrasons dont la fréquence est supérieure à environ 10 MHz. La méthode peut également être utilisée de concert avec des agents facilitant la perméation chimique et/ou avec l'iontophorèse.

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