Ultrasound-enhanced delivery of materials through the skin

A - Human Necessities – 61 – N

Patent

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A61N 7/02 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2196746

A method for enhancing the permeability of the skin or other biological membranes for sampling of physiologic material is disclosed. In this method, ultrasound having a frequency of above about 10 MHz is used to enhance the rate of permeation of physiologic material through the biological membrane and then a diagnostic quantity of the physiologic material is collected. The method may also be used in conjunction with chemical permeation enhancers and/or iontophoresis.

Divulgation concernant une méthode pour améliorer la perméabilité de la peau ou d'autres membranes biologiques, aux fins d'échantillonnage de substances physiologiques. Dans cette méthode, des ultrasons d'une fréquence supérieure à 10 MHz sont utilisés pour améliorer le taux de perméation de substances physiologiques à travers une membrane biologique, lesquelles sont ensuite prélevées en quantités voulues pour le diagnostic. La méthode peut également être employée conjointement à des agents améliorant la perméation chimique et (ou) à l'ionophorèse.

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