Unabridged bis-aryl carbinol derivatives, compositions and...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 401/06 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2132848

2132848 9320063 PCTABS00027 Disclosed is a compound of Formula (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein AR1 represents (a), AR2 represents (b) or a five-membered heterocyclic aromatic group selected from the group consisting of Formulas (I to XII), wherein the substitutable carbon atoms of the five-membered heterocyclic group can optionally be substituted with a group R1. Also disclosed are pharmaceutical compositions containing compounds of Formula (1.0). Further disclosed is a method for treating asthma, allergy and inflammation by administering an anti-asthmatic, anti-allergic or anti-inflammatory, respectively, effective amount of a compound of Formula (1.0).

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