Uncharged morpholino-based polymers having achiral...

Details Uncharged morpholino-based polymers having achiral... Uncharged morpholino-based polymers having achiral...

C - Chemistry, Metallurgy

08

G

C08G 73/06 (2006.01) A61K 47/48 (2006.01) C08G 75/18 (2006.01) C08G 75/20 (2006.01) C08G 75/24 (2006.01) C08G 75/30 (2006.01)

Patent

CA 2069906

A polymer composition is disclosed composed of morpholino subunit structures which are linked together by uncharged achiral linkages. These linkages are one to three atoms in length, joining the morpholino nitrogen of one subunit to the 5' exocyc- lic carbon of an adjacent subunit. Each subunit contains a purine or pyrimidine base-paring moiety effective to bind by hydrogen bonding to a specific base or base-pair in a target polynucleotide.

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