Uncoated pharmaceutical reaction tablet

Details Uncoated pharmaceutical reaction tablet Uncoated pharmaceutical reaction tablet

A - Human Necessities

61

K

A61K 9/46 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2068714

The uncoated compressed reaction tablet for the preparation of an orally applicable aqueous suspension or solution of a pharmaceutically active substances comprises, in a mixture with one another, at least one pharmaceutically active substance, a disintegrant effective amount of at least one water insoluble, water swellable disintegrant and an effervescent effective amount of at least one constituent which generates a gas on reaction with another tablet constituent upon contact with water, both constituents together hereinafter being referred to as "reactants", wherein the weight ratio of disintegrant to reactants is from 0,1 : 1 to 4 : 1, preferably from 0,3 : to 1 :1. At least one reactant preferably reacts more slowly with any one of the other reactancts and/or dissolves more slowly in water than any one of the disintegrants absorbs water.

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