C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01) C12N 15/81 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2349839
The present invention is directed to novel polypeptides having homology to certain human uncoupling proteins ("UCPs") and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention, and methods for producing the polypeptides of the present invention.
L'invention concerne sur de nouveaux polypeptides présentant une homologie avec certaines protéines humaines brûleuses de graisses excédentaires (UCP) et certaines molécules d'acide nucléique codant pour lesdits polypeptides. L'invention concerne également des vecteurs et des cellules hôtes comportant ces séquences d'acide nucléique, des molécules de polypeptide chimériques résultant de la fusion des polypeptides de la présente invention avec des séquences de polypeptides hétérogènes, des anticorps se fixant aux polypeptides de la présente invention, et des procédés d'obtention des polypeptides de la présente invention.
Adams Sean
Pan James
Dennison Associates
Genentech Inc.
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