Underwater pelletizing of active-compound-containing melts

Details Underwater pelletizing of active-compound-containing melts Underwater pelletizing of active-compound-containing melts

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61J 3/06 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2316060

A process for producing pellets comprising biologically active substances in which the biologically active substances are homogeneously dispersed in a matrix based on at least one thermoplastic polymer, which polymer has in aqueous medium a pH-dependent solubility, by homogeneous mixing of the starting materials in the melt and subsequent extrusion and shaping, which comprises the shaping being performed in a cooling medium in which the pellets are not soluble or dispersible.

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