Unipolar electric pulse generator

A - Human Necessities – 61 – N

Patent

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Details

A61N 1/32 (2006.01) C12N 13/00 (2006.01) H03F 3/21 (2006.01) H03K 3/021 (2006.01)

Patent

CA 2629626

Device for improving in vivo penetration of molecules into cells, comprising a generator of square unipolar electric pulses, an electrode device electrically linked to the generator, and a means (8) of injecting the active agent into the tissues. The generator is adapted to generate a signal consisting of a series of square pulses at a low and constant voltage (611) in PWM (Pulse Width Modulation) mode in accordance to the form of the required pulses. The signal is used to divide a constant voltage current (631) output by a direct voltage source (530) and generate a current (641) having a required voltage (130).

La présente invention concerne un dispositif destiné à améliorer la pénétration in vivo de molécules dans des cellules, comprenant un générateur d~impulsions électriques unipolaires carrées, une électrode reliée électriquement au générateur et un moyen (8) d~injection de l~agent actif dans les tissus. Le générateur est conçu pour générer un signal consistant en une série d~impulsions carrées à une tension faible et constante (611) en mode MID (modulation d~impulsions en durée) selon la forme des impulsions requises. Le signal est utilisé pour diviser un courant de tension constante (631) sorti par une source de tension directe (530) et générer un courant (641) ayant une tension requise (130).

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