C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/245 (2006.01) A61K 39/42 (2006.01) C07H 21/00 (2006.01) C07K 14/03 (2006.01) C07K 16/08 (2006.01) C07K 19/00 (2006.01) C12N 7/00 (2006.01) C12N 9/96 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2196892
This invention provides an isolated DNA molecule which is at least 30 nucleotides in length and which uniquely defines a herpesvirus associated with Kaposi's sarcoma. This invention provides an isolated herpesvirus associated with Kaposi's sarcoma. This invention provides an antibody specific to the peptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a method of vaccinating a subject for KS, prophylaxis diagnosing or treating a subject with KS and detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
Molécule d'ADN isolée dont la longueur comporte au moins 30 nucléotides et qui définit de manière unique un herpèsvirus associé à la maladie de Kaposi. La présente invention concerne un herpèsvirus isolé associé à la maladie de Kaposi. La présente invention concerne encore un anticorps spécifique du peptide. Des molécules d'oligonucléotides antisens et triplex sont également décrites. La présente invention concerne en outre un procédé de vaccination d'un sujet contre la maladie de Kaposi, de diagnostic à des fins prophylactiques ou de traitement d'un sujet atteint de la maladie de Kaposi et de détection de l'expression d'un virus à ADN associé à la maladie de Kaposi dans une cellule.
Chang Yuan
Moore Patrick S.
Gowling Lafleur Henderson Llp
The Trustees Of Columbia University
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