Unit doses, aerosols, kits, and methods for treating heart...

A - Human Necessities – 61 – K

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A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61P 9/06 (2006.01)

Patent

CA 2755809

Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated.

L'invention concerne des méthodes pour traiter une arythmie atriale consistant à administrer une quantité efficace d'au moins un agent pharmaceutique antiarythmique à un patient qui en a besoin, de sorte qu'au moins l'agent pharmaceutique antiarythmique entre dans le cur via la veine pulmonaire puis dans l'oreillette gauche. D'autres méthodes de traitement de l'arhythmie atriale consistent à adiministrer par inhalation une quantité efficace d'au moins un agent pharmaceutique antiarythmique à un patient qui en a besoin. Une quantité de l'agent pharmaceutique antiarythmique peut former un pic dans le sinus coronaire du cur pendant une durée comprise entre 10 secondes et 30 minutes à partir du début de l'administration. L'invention concerne également des doses unitaires, des aérosols, et des trousses.

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