Universal coronavirus vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/50 (2006.01) A61K 39/215 (2006.01) C07K 14/165 (2006.01) C07K 16/10 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2135201

2135201 9323421 PCTABS00028 A universal vaccine is disclosed which elicits a protective immune response in different host species and against different coronaviruses. A polypeptide which elicits protective antibodies against a homologous sequence found in the C terminal portion of coronavirus S proteins is disclosed. Vaccines comprising either the polypeptide or nucleic acids which encode the polypeptide are also disclosed. Methods of protecting a host against coronavirus infection are disclosed.

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