Universal t-cell epitopes for anti-malarial vaccines

Details Universal t-cell epitopes for anti-malarial vaccines Universal t-cell epitopes for anti-malarial vaccines

A - Human Necessities

61

K

A61K 38/10 (2006.01) A61K 39/002 (2006.01) A61K 39/015 (2006.01) A61K 39/295 (2006.01) C07K 7/08 (2006.01) C07K 14/445 (2006.01)

Patent

CA 2278295

The present invention provides methods and compositions for eliciting protective immunity against malaria. In particular, the invention relates to universal T-cell epitopes that elicit T-cell responses in individuals of differing genetic backgrounds. Immunogenic compositions and vaccines comprising malaria-specific universal T-cell epitopes are disclosed.

La présente invention concerne des procédés et des compositions destinés à produire une bonne immunité contre la malaria. Cette invention concerne notamment des épitopes universels des lymphocytes T qui déclenchent des réponses des lymphocytes T chez des individus ayant différents antécédents génétiques. L'invention concerne également des compositions immunogènes et des vaccins comprenant des épitopes universels des lymphocytes T spécifiques de la malaria.

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