G - Physics – 01 – N
Patent
G - Physics
01
N
167/44, 150/8, 1
G01N 33/553 (2006.01) C07H 23/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/532 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01)
Patent
CA 1335254
An aggregate for qualitatively or quantitatively determinable bindable substances. Said aggregate comprises an ultra small colloidal particle and a specific binding agent characterized in that the mean diameter of the colloidal particle is below 2 nm. Preferably the size of the metal particle is selected so that the aggregate is capable of penetrating in standard biological specimens. The invention further provides a universally applicable detection system for determining bindable substances in particular in living material. Further there is provided a process for preparing said aggregate.
583084
de Brabander Marc J.
Leunissen Johannes L. M.
Van de Plas Petrus F. E. M.
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Naamloze Vennootschap
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