Unsaturated amino acids

Details Unsaturated amino acids Unsaturated amino acids

C - Chemistry, Metallurgy

07

F

167/250, 167/261

C07F 9/38 (2006.01) A61K 31/66 (2006.01) C07F 9/30 (2006.01) C07F 9/32 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1331625

Unsaturated amino acids Abstract The invention relates to unsaturated amino acids of the formula I Image (I) in which R1 represents hydroxy or etherified hydroxy, R2 represents hydrogen, alkyl, hydroxy or etherified hydroxy, R3 represents hydrogen, alkyl, haloalkyl, hydroxyalkyl, lower alkoxyalkyl, arylalkyl, lower alkenyl, halogen or aryl, R4 represents hydrogen, alkyl or aryl, R5 represents hydrogen or alkyl, R6 represents carboxy or esterified or amidated carboxy, R7 represents amino or amino substituted by alkyl or acyl, A represents unsubstituted or alkyl-substituted .alpha.,.omega.-alkylene having from 1 to 3 carbon atoms or represents a bond, and B represents methylene or a bond, with the proviso that A is other than a bond when B represents a bond, and salts thereof. They can be manufactured, for example, in accordance with the Michaelis-Arbuzov reaction and can be used as pharmacologically active substances.

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